Mika en U.N.K.L.E. op Lowlands

Alle tot nu toe bevestigde muziekacts op het Lowlandsprogramma zijn:
Arcade Fire, Admiral Freebee, After Forever, Air Traffic, Alamo Race Track, Lily Allen, The Answer, Devendra Banhart, Basement Jaxx, Battles, Bonde Do Role, Brand New, CSS, Chatham County Line, CocoRosie, Chris Cornell, Dinosaur Jr., Eagles of Death Metal, Editors, Enter Shikari, Funeral for a Friend, Laurent Garnier (live), The Good, The Bad & The Queen, Groove Armada, Hayseed Dixie, Heideroosjes, Interpol, Jamie T, Jimmy Eat
World, Justice (live), Just Jack, Kasabian, Kaiser Chiefs, The Killers, Kings of Leon, Klaxons, Lacuna Coil, La Kinky Beat, LCD Soundsystem, Little Cow, Loney, dear, Mad Caddies, M.I.A., Mika, Motörhead, My Brightest Diamond, New Young Pony Club, Nine Inch Nails, Nosfell, Nour, Oi Va Voi, Ojos de Brujo, Orishas, Jack Peñate, Peter, Bjorn and John, Pronghorn, The Rakes, Damien Rice, The Rifles, Rodrigo y Gabriela, Rotfront, Saybia, The Shins, Sonic Youth, Tanya Stephens, Tool, Turbonegro, U.N.K.L.E.,
The View, Patrick Watson, Welle:Erdball, The Whitest Boy Alive, Patrick Wolf.

Naast muzikale acts zijn ook reeds namen op het literatuur-, comedy- en Lowlands University programma.
Bevestigd zijn;
Pieter van Vollenhoven, Kluun & Saskia Noort, Jan Jaap van der Wal, De Lamas, Danger Zone, Steve Rawlings, Guido Weijers, A Night of Comedy (Bob MacLaren, Patrick Laureij, Steven Stol, Bram van der Velde en Martijn Oosterhuis), Doug Stanhope, The Unbookables, Ronald Goedemondt, Arj Barker, Comedytrain.